Clonazepam is a potent, long-acting benzodiazepine medication that is FDA-approved for treating certain seizure disorders and panic disorder in adults . It is available as a generic drug and under the brand name Klonopin, in both oral tablets and orally disintegrating tablets . The drug was first approved by the FDA in June 1975 .
Mechanism of Action
Clonazepam works by enhancing the activity of GABA, the major inhibitory neurotransmitter in the central nervous system . It acts as a positive allosteric modulator of GABA-A receptors, increasing the frequency of chloride channel opening, resulting in neuronal hyperpolarization and reduced firing .
